Could This Be the Initial Indicator of Memory Decline?
Written by Susan Parker | Updated on May 28, 2025
Reviewed by Susan Parker
Key Takeaways
Temporalis muscles may predict dementia early.
Routine brain MRIs already capture muscle data.
Preventing muscle loss could protect brain health.
Frequently Asked Questions
Key Takeaways
Temporalis muscles may predict dementia early.
Routine brain MRIs already capture muscle data.
Preventing muscle loss could protect brain health.
Frequently Asked Questions
You might think that memory loss is the first sign of dementia, but what if there's an unexpected early warning...
New studies have identified a surprising predictor that could show up years before cognitive symptoms appear. The exciting news is that this predictor can be spotted on routine medical scans that most older adults receive.
Usually, when considering early dementia detection, symptoms like memory loss, confusion, and agitation are top of mind.
However, these signs typically show up only after the disease has already affected the brain significantly. New research on early memory loss detection suggests that in addition to focusing on cognitive function, healthcare providers should also pay attention to muscle tone, particularly the tone and size of a muscle near the brain.
In a recent study by researchers at Johns Hopkins University School of Medicine, muscle loss in the temporalis muscles — located in the head — of 621 seniors without dementia was measured using MRI1. Participants were divided into groups with either large or small temporalis muscles.
Nearly six years later, the same participants underwent evaluations for cognitive function, dementia, and changes in brain volume. The results showed that individuals in the small temporalis group were more likely to have developed dementia compared to the initial study.
“Our study discovered that older adults with smaller skeletal muscles have about a 60% higher risk of developing dementia, even after accounting for other known risk factors,” said Marilyn Albert, Ph.D., co-senior author of the study and a neurology professor at Johns Hopkins.
While a 60% increase in the risk of developing this life-altering disease is significant, being informed about this risk early on could make a significant difference in your future.
The researchers emphasize that testing for muscle loss can be quickly done through a standard brain MRI, even if the imaging was done for other reasons.
“Measuring temporalis muscle size as a possible indicator for overall skeletal muscle status offers a chance for skeletal muscle assessment without extra cost or burden in older adults who already undergo brain MRIs for neurological conditions like mild dementia. This study is the first to demonstrate over time that skeletal muscle loss may contribute to dementia development,” stated Kamyar Moradi, M.D., lead author of the study and a postdoctoral research fellow at Johns Hopkins University School of Medicine.
In the long run, this test could help patients save time and money, and it could assist in identifying individuals who could benefit from early interventions to stop or slow memory loss.
Other studies have linked muscle health to declining brain health, with the encouraging news being that in many cases, muscle loss can be reversed.
Staying physically active is one way to prevent muscle loss and promote muscle growth. You don’t need to engage in intense workouts to see improvements. Activities like gardening, cleaning, walking, and cycling can help maintain strong and healthy muscles.
Nutrition is also vital for muscle upkeep. Consuming enough protein can help maintain and build muscle mass. Additionally, nutrients like choline and B vitamins are crucial for muscle health.
Supplements like HMB (beta-hydroxy beta-methylbutyrate) can also be beneficial as they help preserve and rebuild muscle mass. Clinical studies have shown that HMB supplementation can enhance muscle function, improve physical performance, and reduce the risk of falls — all essential aspects for healthy aging and a high quality of life.
If you are worried about your muscle health, consult your healthcare provider about undergoing testing for muscle loss and the most effective ways to prevent it.
A groundbreaking study from Johns Hopkins suggests that diminishing head muscles — especially the temporalis muscle — might predict dementia years before traditional symptoms like memory loss and confusion show up. Through routine brain MRIs, researchers found that individuals with smaller temporalis muscles had a 60% higher chance of developing dementia. This discovery not only offers hope for early detection but also shows how simple lifestyle changes such as exercise and nutrition could protect both your muscles and your brain.
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