Discover the age-old secret to anti-aging: Cycloastragenol and its supplement.
Written by Susan Parker | Updated on May 28, 2025
Reviewed by Susan Parker
Key Takeaways
Cycloastragenol has anti-aging and immune-boosting properties
Supplementation with cycloastragenol supports telomere health, reduces inflammation, and lowers oxidative stress
Cycloastragenol activates telomerase to maintain telomere length
Frequently Asked Questions
Key Takeaways
Cycloastragenol has anti-aging and immune-boosting properties
Supplementation with cycloastragenol supports telomere health, reduces inflammation, and lowers oxidative stress
Cycloastragenol activates telomerase to maintain telomere length
Frequently Asked Questions
If you're seeking natural ways to combat aging and boost your immune system, Traditional Chinese Medicine holds a fascinating solution in cycloastragenol and its supplements. This potent compound, derived from Astragalus membranaceus plant roots, is renowned for its anti-aging and immune-enhancing properties. Let's delve into the ancient wisdom surrounding cycloastragenol and how incorporating this supplement can enhance your overall well-being and longevity.
Cycloastragenol, a plant extract, is known for its anti-aging and immune-boosting effects.
Supplementing with cycloastragenol can aid in maintaining telomere health, reducing inflammation, and lowering oxidative stress, thereby promoting better overall health.
The primary action of cycloastragenol revolves around its ability to activate telomerase, a crucial enzyme for preserving telomere length, the protective caps at the end of chromosomes.
Cycloastragenol is sourced from Astragalus membranaceus roots, also known as astragalus root and Mongolian milkvetch. Dating back to 200 AD and early Traditional Chinese Medical texts, the medicinal use of Astragalus membranaceus plant roots has a history of 1,800 years. While ancient Chinese healers utilized dried astragalus roots under the name Huangqi for health preservation, the discovery of cycloastragenol was unknown to them. Cycloastragenol belongs to the triterpenoid group of plant compounds, known for their antimicrobial properties. In humans, cycloastragenol showcases potent anti-inflammatory, antiviral, and immune-boosting characteristics, making it a staple in Traditional Chinese Medicine for centuries.
The primary compound in Astragalus membranaceus is astragaloside IV, abundant in amino acids. Both astragaloside IV and cycloastragenol share a similar chemical structure, differing only in two sugar groups. However, when it comes to anti-aging benefits, cycloastragenol demonstrates exceptional potential. Recent research featured in the journal Advances in Pharmacology highlights cycloastragenol's ability to:
Enhance and regulate the immune system
Support optimal blood pressure levels
Enhance cardiovascular health
Boost cellular health
Facilitate liver health
Aid in wound healing processes
These diverse effects position cycloastragenol as a promising anti-aging supplement. The question arises: how does cycloastragenol deliver these wide-ranging benefits? Research indicates that cycloastragenol exerts numerous positive actions and benefits within the body, functioning by:
Combating free radicals and lowering oxidative stress associated with aging
At its core, the primary mode of action of cycloastragenol lies in its telomerase activation ability, crucial for maintaining telomere length.
Telomeres act as protective caps on chromosome ends, safeguarding them from deterioration. As cells divide, telomeres naturally shorten, eventually leading to DNA damage and cellular aging as they lose their protective capability. Telomerase, a ribonucleoprotein complex, elongates telomeres, potentially delaying the aging process. Cycloastragenol stands out as one of the limited natural telomerase activators, drawing significant attention for its ability to potentially slow down aging.
The telomerase activation by cycloastragenol is believed to be linked to the MAPK and PI3K/Akt signaling pathways. Studies have demonstrated that cycloastragenol can activate telomerase and lengthen telomeres in a telomerase-dependent manner, as evidenced in cell and clinical studies. This telomerase activation holds promise in maintaining telomere length and delaying cellular aging.
Beyond preserving telomere length, research also indicates that cycloastragenol can:
Enhance antioxidant activity by elevating Nrf-2, a transcription factor regulating antioxidant protein expression
Shield cells from oxidative stress
Help prevent age-related degenerative processes triggered by oxidative stress
When compared to other telomerase activators, the small molecular size and favorable bioavailability of cycloastragenol make it an optimal supplement choice, requiring lower doses for efficacy. This distinguishing feature sets cycloastragenol apart from other compounds that might demand higher doses to achieve comparable results.
The immune system serves as the body's frontline defense against pathogens, viruses, and bacteria. A weakened immune system can render you susceptible to frequent cold viruses, while an overactive immune response may lead to chronic inflammation and autoimmune conditions.
Cycloastragenol has demonstrated its ability to bolster immune function. One way in which cycloastragenol supports the immune system is by activating telomerase and fostering T lymphocyte proliferation. T lymphocytes, commonly known as T-cells, are vital components of the adaptive immune system, responsible for identifying and eliminating infected or abnormal cells. By stimulating T-cell proliferation, cycloastragenol may contribute to maintaining a resilient and responsive immune system.
Various studies have corroborated the immune-boosting properties of cycloastragenol, consistently showcasing its ability to fortify immune function by enhancing telomere health and diminishing inflammation. Consequently, incorporating cycloastragenol supplements into your immune-support regimen could prove beneficial.
Cycloastragenol also plays a role in maintaining a robust and healthy heart. Its potential to support cardiovascular health may stem from its influence on the FXR signaling pathway. Animal studies suggest that cycloastragenol helps reduce lipid accumulation in the liver under high-fat diet conditions. This reduction aids in regulating blood sugar levels, blood fats (triglycerides), and liver enzymes (hepatic bile acids). By enhancing liver function and lipid metabolism, cycloastragenol can facilitate improved blood circulation, promote healthier blood vessels and arteries, and enhance overall cardiovascular system health.
Another factor contributing to heart health is the impact of cycloastragenol on proteasome activity. Proteasomes play a vital role in preserving cellular health by breaking down damaged or misfolded proteins. This heightened proteasome activity may help shield the heart and blood vessels from oxidative stress and inflammatory harm.
Aside from its direct effects on cardiovascular health, cycloastragenol shows promise in supporting healthy aging and immune function, indirectly benefitting heart health. By nurturing telomere and cellular health, reducing inflammation, and enhancing immune function, cycloastragenol supplements can play a role in upholding cardiovascular well-being and overall vitality.
Cycloastragenol supplements are available in diverse forms, offering varying concentrations of this potent compound. To maximize the benefits of your cycloastragenol supplement, it's crucial to grasp the available supplement types, recommended dosages, and safety considerations.
Cycloastragenol supplements are accessible in multiple formats, including capsules, tablets, and liquid extracts. Capsules and tablets typically emerge as the most convenient and easily administered options, formulated to optimize cycloastragenol absorption and bioavailability in the body.
The recommended dosage for cycloastragenol supplements varies depending on individual health needs and desired outcomes. A common suggestion entails taking one 100mg capsule daily. Dosage recommendations may vary based on age and existing health conditions. Consultation with a healthcare provider is advisable for personalized guidance tailored to your specific requirements.
developed featuring a scientifically validated cycloastragenol dosage to uphold healthy telomeres and enhance your well-being as you age gracefully. stands out by incorporating a Telomerase Activation Complex sourced from extensively researched natural telomerase activators, scientifically proven to aid in cellular rejuvenation. These components include:
Cycloastragenol (CAG): A staple in Traditional Chinese Medicine, supporting telomerase activation, lipid metabolism improvement, immune system enhancement, and possessing potent anti-inflammatory and antioxidant attributes.
Telos95: A potent antioxidant blend of organic grapevine and olive leaves, demonstrating efficacy in slowing down telomere shortening, potentially retarding the aging process in healthy cells. Research at Princeton Consumer Research suggests that a year-long consumption of Telos95 may reduce telomere biological age by over seven years.
Alpha Lipoic Acid (ALA): An endogenous antioxidant facilitating glucose-to-energy conversion. Studies from Emory University School of Medicine indicate ALA's potential in stimulating telomerase.
Additionally, you stand to benefit from:
Pterostilbene: A polyphenolic compound naturally found in plants, primarily in blueberries, known for reducing age-related inflammation and supporting optimal telomere length. Italian laboratory investigations suggest that pterostilbene may contribute to longevity through varied mechanisms still under exploration.
CoQ10: A vital coenzyme aiding mitochondria in energy production for cells. National Institute on Aging research indicates that this essential antioxidant can alleviate aging symptoms and enhance cellular bioenergetics.
Grape Seed extract: Possessing double the antioxidant capacity of red wine extract (resveratrol), grape seed extract is rich in resveratrol content. Resveratrol significantly boosts telomerase activity. Grape seed extract demonstrates efficacy in improving cholesterol markers, reducing blood pressure, combating inflammation, potentially lowering heart disease risk, protecting against age-related genetic neural and cerebral damage, and supporting immune system functionality during aging.
Vitamin D: Research indicates that adequate vitamin D levels may decelerate cellular DNA aging, collaborating with telomerase to maintain telomere length. Furthermore, maintaining optimal vitamin D levels in aging individuals may reduce the risk of cognitive decline, depression, osteoporosis, heart disease, diabetes, and cancer. Epidemiological studies underline that older individuals with insufficient Vitamin D levels are at higher risk for these health conditions.
Vitamin K2 (menaquinone): Extensive research showcases Vitamin K2's role in activating vital protective proteins, benefiting age-related health concerns. These proteins contribute to maintaining arterial health, bolstering bone strength, supporting cognitive sharpness, enhancing insulin sensitivity, and potentially lowering cancer risk.
Cycloastragenol, an esteemed component in Traditional Chinese Medicine derived from Astragalus membranaceus roots, offers distinctive advantages for enhancing health and aging gracefully. Its telomerase activation, cellular health promotion, immune system fortification, and anti-inflammatory properties position it as a promising supplement for overall health improvement. Serving as the cornerstone of the anti-aging supplement , cycloastragenol emerges as a valuable addition to your daily health routine.
As the realm of cycloastragenol research unfolds further, additional insights into its potential benefits and applications are poised to emerge. Nevertheless, this ancient root holds promise in supporting your health and vitality, propelling you towards a path of radiant well-being and longevity.
Cycloastragenol exhibits capabilities in reversing visible signs of aging, enhancing immune and heart health, boosting physical endurance, and improving bone density. Thus, it appears to offer numerous positive effects in counteracting the aging process.
Cycloastragenol aids in maintaining healthy telomere length by elevating telomerase levels in the body. Additionally, B vitamins like folate and vitamin B12 contribute to telomere repair. Studies have established positive associations between the use of B vitamins and telomere length, with higher-than-normal vitamin B12 levels achieved through supplementation demonstrating potential in decreasing inflammation and oxidative stress, potentially explaining the extended telomeres linked to its intake.
Astragalus root extract contains 10% cycloastragenol, equating to 20mg per capsule. This underscores why anti-aging experts recommend opting for a cycloastragenol supplement like that delivers significantly higher quantities. offers a Telom