Looking to Shed Pounds? Stay Away from This Artificial Sweetener…
Written by Susan Parker | Updated on May 28, 2025
Reviewed by Susan Parker
Key Takeaways
Artificial sweeteners may harm metabolic health.
Some sweeteners affect liver detoxification.
Avoid artificial sweeteners for better health.
Not all artificial sweeteners are safe.
Artificial sweeteners may not aid weight loss.
High consumption of sweeteners can lead to health problems.
Limit sweeteners intake for better health.
Opt for water or unsweetened drinks.
Balance sweetener consumption with caution.
Avoid sugar and artificial sweeteners.
Moderation is key with sweeteners.
Be cautious of sweetened products.
Choose healthier drink alternatives.
Sweeteners can affect blood sugar levels.
Consider sweeteners as an occasional treat.
Frequently Asked Questions
Key Takeaways
Artificial sweeteners may harm metabolic health.
Some sweeteners affect liver detoxification.
Avoid artificial sweeteners for better health.
Not all artificial sweeteners are safe.
Artificial sweeteners may not aid weight loss.
High consumption of sweeteners can lead to health problems.
Limit sweeteners intake for better health.
Opt for water or unsweetened drinks.
Balance sweetener consumption with caution.
Avoid sugar and artificial sweeteners.
Moderation is key with sweeteners.
Be cautious of sweetened products.
Choose healthier drink alternatives.
Sweeteners can affect blood sugar levels.
Consider sweeteners as an occasional treat.
Frequently Asked Questions
Many individuals think that including artificial sweeteners in their diet is a healthy choice, helping with weight control and blood sugar management. However, research on the effects of these substances raises concerns.
Throughout the years, there has been talk about the potential link between artificial sweeteners and cancer. Nevertheless, recent studies indicate that artificial sweeteners might not aid in weight loss and could potentially lead to other health issues.
Here is what you need to know...
The most recent research suggests that certain artificial sweeteners could disrupt metabolic health and hinder the liver's ability to detoxify the body. These studies also show that these substances do not affect health uniformly, with some presenting a higher risk than others.
Researchers at the Medical College of Wisconsin have found that two common artificial sweeteners can interfere with the liver's usage of a vital protein involved in detoxification and drug breakdown.
"With around 40% of Americans regularly consuming non-nutritive sweeteners, it is crucial to understand their impact on the body," warned Laura Danner, a researcher at Wisconsin. "Many people are unaware that these sweeteners are present in sugar-free products like yogurts, snacks, liquid medications, and even certain cosmetics."
The Wisconsin study reveals that acesulfame potassium and sucralose disrupt the functioning of PGP (P-glycoprotein) in the body. PGP is part of a group of transporters that assist the liver in removing toxins, drugs, and their byproducts.
Their findings suggest that these sweeteners "influence liver detoxification."
"We observed that sweeteners impacted PGP activity in liver cells at levels commonly found in everyday foods and beverages, well below the FDA's recommended maximum limits," said Stephanie Olivier-Van Stichelen, PhD, who heads the research team. "To our knowledge, we are the first to reveal how non-nutritive sweeteners affect liver detoxification at a molecular level."
The researchers caution that this effect on the liver could create a detoxification challenge for individuals taking antidepressants, blood pressure medications, and antibiotics.
Other studies have pointed out additional concerns regarding specific artificial sweeteners: saccharin and sucralose can impact the body's glycemic response, affecting the fluctuation of blood sugar levels after meals.
According to researchers at the Weizmann Institute of Science and the German National Cancer Center, these artificial sweeteners can alter the types of beneficial bacteria in the gut, disrupting the body's blood sugar regulation. The long-term effects of these changes are still uncertain, but the findings are concerning.
Moreover, saccharin has been associated with increased weight gain.
Despite artificial sweeteners being marketed as weight loss aids due to their lack of calories, several studies have shown that they are not effective in helping individuals maintain weight loss.
Recent research at Purdue University suggests that consumers of saccharin might be more susceptible to weight gain, although the exact reasons for this trend are not yet clear.
All evidence points to the advice to steer clear of artificial sweeteners if you are worried about your health.
Avoiding these sweeteners does not mean you should increase your sugar intake. Many researchers studying sweeteners caution that sugar poses similar risks to weight and health.
As suggested by Eran Elinav, MD, PhD, from the Weizmann Institute of Science: "Sugar consumption remains a well-established health risk for obesity, diabetes, and other health issues, and our findings do not support sugar consumption. However, the effects of sweeteners we have identified indicate a cautious approach is necessary."
Dr. Elinav and I recommend reducing sweetener intake as much as possible, using them only occasionally. It is especially important to avoid sweetened drinks and choose water instead. Water, unsweetened tea, and coffee are the safest options.
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