Old Herb that Relieves Joint Problems and Reduces Inflammation
Written by Susan Parker | Updated on May 28, 2025
Reviewed by Susan Parker
Key Takeaways
Milk Thistle fights inflammation
Silymarin supports heart health
Milk thistle enhances sleep
Frequently Asked Questions
Key Takeaways
Milk Thistle fights inflammation
Silymarin supports heart health
Milk thistle enhances sleep
Frequently Asked Questions
Imagine if a single plant could aid in safeguarding your joints and heart, while also enhancing your sleep quality?
An age-old herb seems to be stepping up to the challenge.
The scientific community is abuzz with excitement over the potent anti-inflammatory and antioxidant properties of this traditional herb. Let's explore how it can benefit you...
Milk thistle (Silybum marianum) has been utilized for generations as a natural remedy, with its roots tracing back to ancient civilizations such as Greece, Rome, and Egypt.
The earliest documented instances of its medicinal use date back to Dioscorides, a Greek physician in the 1st century AD, who highlighted its efficacy in treating liver disorders and detoxifying the body.
This plant, distinguished by its purple flowers and spiky leaves, was highly esteemed by medieval herbalists who believed it could shield the liver from toxins, including snake bites and alcohol consumption. Over time, European monks integrated milk thistle into their medicinal gardens, employing it in the treatment of jaundice, gallbladder ailments, and digestive issues.
During the Renaissance era, milk thistle's reputation as a liver tonic continued to flourish, with physicians prescribing it for conditions like hepatitis and cirrhosis. In the 19th and early 20th centuries, folk medicine practitioners in Europe and North America recommended milk thistle for a variety of ailments, from indigestion to inflammation. It was commonly used as a remedy for "liver stagnation," a term from traditional herbal medicine describing sluggish liver function and toxin accumulation. As herbal medicine advanced, milk thistle became a cornerstone of detox protocols, believed to aid the body in recovery from excessive food and alcohol consumption.
Modern research has validated many traditional uses of milk thistle, confirming its role in liver protection and its potent antioxidant properties. Studies conducted in the 20th and 21st centuries have pinpointed silymarin, the active component in milk thistle, as the primary driver behind its therapeutic effects.
While initial medical investigations focused on liver-related issues, recent studies are exploring the potential benefits of milk thistle in alleviating joint pain, addressing metabolic concerns, and bolstering the immune system.
Ongoing research is examining how silymarin, comprising the natural chemical silibin and other antioxidants, can combat chronic inflammation, mitigate immune cell dysfunction, which can harm organs and joints, and alleviate pain in daily life.
When inflammation is triggered by the immune system, immune cells go into high alert mode, embarking on a mission to seek out and eliminate invading pathogens, and neutralize threats to the body. To regulate inflammation, signals within cells instruct immune cells to stand down once the danger has passed.
However, if these signals fail, the immune system can become "dysregulated," resulting in rogue immune cells that perpetuate chronic inflammation over extended periods.
According to a group of European researchers, silymarin has shown promise in dampening inflammation by acting as an antioxidant and boosting the body's chemical messengers that signal immune cells to calm down, thereby aiding in better regulation of inflammation.
By curbing inflammation, silymarin also modulates cytokines – signaling molecules in the bloodstream – that would otherwise prompt immune cells to inflame, attack, and damage joints. A study in the Middle East illustrates silymarin’s protective effects on knees from osteoarthritis.
Additionally, a review from Wright State University Boonshoft School of Medicine in Ohio provides further evidence that silymarin in milk thistle can alleviate joint discomfort. The analysis indicates that silymarin has the potential to ease the pain caused by an overactive immune system, joint wear and tear, and prevent future joint damage.2
Studies also reveal that silymarin can:
Depending on your health objectives, silymarin could serve as the antioxidant and anti-inflammatory herb you need for better health. There are various ways to consume milk thistle, and the most suitable method depends on your health targets:
A clinical dose of the most potent form of silymarin, combined with two other anti-inflammatory ingredients, is included in Triple Joint Relief formula.
Recommended dosages may vary based on the specific condition being addressed. As per natural health practitioners' general guidelines:
The optimal time to take milk thistle and silymarin is with meals, as silymarin is fat-soluble and absorbs better when consumed with meals containing healthy fats like avocados, nuts, or olive oil. It is also advisable to split your milk thistle doses throughout the day, taking smaller doses with meals instead of one large dose.
Milk thistle, renowned for its liver-protective properties, is now acknowledged for a broad spectrum of health benefits extending beyond liver detoxification. Research indicates that silymarin, the active compound in milk thistle, can alleviate chronic inflammation, offering potential relief for joint pain, diabetes, high blood pressure, metabolic syndrome, and sleep disorders. By modulating immune responses, silymarin prevents inflammatory damage and shields the joints, heart, and nervous system. Moreover, studies suggest that it enhances insulin sensitivity, lowers blood sugar levels, and promotes a balanced gut microbiome for overall well-being.
What is silymarin, and how does it differ from milk thistle?
Milk thistle (Silybum marianum) is a plant known for its health benefits, particularly in liver support. Silymarin is the active compound extracted from milk thistle seeds, responsible for its medicinal properties. Silymarin, a potent antioxidant and anti-inflammatory agent, aids in protecting liver cells, regulating blood sugar, and reducing chronic inflammation.
How does silymarin benefit liver health?
Silymarin strengthens liver cell membranes, shielding them from toxins such as alcohol, medications, and environmental pollutants. It also supports liver regeneration, aids in detoxification, and reduces oxidative stress, benefiting conditions like fatty liver disease, hepatitis, and cirrhosis.
Can milk thistle or silymarin help manage high blood sugar?
Research suggests that silymarin improves insulin sensitivity and helps regulate blood sugar levels. By enhancing insulin receptor function and reducing inflammation associated with insulin resistance, silymarin has shown to lower fasting blood sugar and HbA1c levels in individuals with type-2 diabetes.
Is milk thistle safe for daily consumption?
Milk thistle is generally safe for most individuals when taken in recommended doses. However, individuals with ragweed allergies, hormone-sensitive conditions, or those on blood thinners or diabetes medications should consult a healthcare provider before use. Mild side effects like digestive discomfort or headaches may occur in some individuals.
How long does it take to experience silymarin benefits?
The timeline for experiencing silymarin benefits depends on dosage, consistency, and the health condition being addressed. Some individuals may notice improved digestion and mild detox effects within days, while enhancements in liver health, reduced inflammation, and blood sugar regulation may take weeks to months of consistent usage.
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